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An early publication in the Annals of the New York Academy of Sciences documenting the original discovery of telomere shortening as a primary mechanism of cellular senescence and its relevance to human aging biology provides the foundational framework for understanding why telomerase-activating compounds attract longevity research attention

doi: 10.1111/j.1468-2982.2007.01288.x 2

The small molecule has also been shown to help lower blood cholesterol levels and stimulate muscle repair in animal studies, paving the way for a host of research applications