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The incorporation of -methyl leucine at position 13 serves as a key structural element that enhances both glucose-dependent insulinotropic polypeptide and glucagon receptor activation while maintaining glucagon-like peptide-1 receptor affinity [7] [9]

Wegovy injections are done with a single-use auto injector, while Zepbound is available as a single-use auto injector, in a single-use vial that is administered via syringe, or in a new device called a KwikPen that can deliver several doses before it is discarded

The implementation of this approach leads to improved safety and effectiveness for large-molecule pharmaceuticals

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