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An earlier and arguably more influential paper from three Indian dermatologists, published in the Indian Journal of Dermatology, Venereology and Leprology , identified three randomised controlled trials supporting a skin-lightening effect and a good safety profile for topical and oral glutathione specifically

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protein also called adrenodoxin reductase) in the transfer of electrons from NADPH to the cytochrome P450.

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For this reason, it can be used in athletes and post-surgery patients

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