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Older Adults: As we age, the bodys ability to absorb B12 decreases, making supplementation important for older adults

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Adding pathways adds mechanisms: tirzepatide outperforms semaglutide because two pathways work better than one, and retatrutide may outperform tirzepatide because three pathways address both caloric intake (appetite) and caloric output (energy expenditure) simultaneously

While some studies suggest these sweeteners can help people reduce overall calorie intake, others have found that some people may compensate by eating more later or experience stronger cravings for sweet foods