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13,79 The results of the pooled data show a significant improvement with NAC in the Aberrant Behaviour Checklist (based on four studies), whilst no improvement was seen in the Repetitive Behaviour Scale (two studies), and improvements in the Social Responsiveness Scale (two studies) failed to reach statistical significance
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Peripheral blood neutrophil death in patients and SLE-prone mice could be inhibited by classical ferroptosis inhibitors, liproxstatin-1, and deferoxamine, while necroptosis and apoptosis inhibitors had relatively less effect on neutrophils, confirming that ferroptosis is the predominant neutrophil death pathway in SLE patients
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