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Biologics including protein-based therapies and vaccines are more complex and contain larger molecules

Safety Profile and Contraindications General Side Effects: As a class, GLP-1 RAs are generally well-tolerated, with the most common adverse effects being gastrointestinal symptoms due to slowed gastric emptying and central appetite effects

In one of the recent studies by researchers from the University Hospitals in Cleveland, for instance, 0.1% of obese people prescribed a GLP-1 drug to lose weight developed gastroparesis six months or more later, compared to 0.04% of similarly matched patients who werent prescribed a GLP-1

An additional annual weight loss of 5.35.9 kg has been observed compared with placebo [11, 17,18,19]