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In vitro organoid studies: Murine and human intestinal organoids were used to study molecular mechanisms

Under normal conditions, their contents and distributions are in dynamic equilibrium, which is vital for cell survival [51]

Certain subclasses display mechanistic preferences: polyphenols like resveratrol and curcumin frequently downregulate nuclear factor kappa B (NF-B) and signal transducer and activator of transcription 3 (STAT3), impairing inflammatory and survival cascades (Melim et al., 2022)