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In the TRIUMPH-1 obesity trial, patients on the highest dose lost an average of about 28% of their body weight at 80 weeks, and a subgroup with higher starting weight lost up to about 30% at 104 weeks

Employers and health plans increasingly recognize that reducing out-of-pocket costs for effective treatments improves adherence, health outcomes, and overall workforce productivity

Neuroimaging research in obesity populations indicates these medications reduce activation in brain regions associated with food reward and craving (Ten Kulve et al., 2016), potentially addressing the compulsive nature of binge eating

The advantage: Azelaprag is administered orally, so taking it alongside a GLP-1 agonist wouldnt be much of a burden for patients