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Some naturopathic physicians and sports medicine specialists have developed expertise in this area, though finding knowledgeable practitioners may require research depending on location

No human safety data : The complete absence of human clinical trials means the safety profile, side effects, optimal dosing, and pharmacokinetics in humans are entirely unknown Animal-to-human translation is uncertain : Metabolic differences between mice and humans mean that the magnitude of effects (e.g., weight loss, grip strength improvement) may not translate

Antioxid Redox Signal 16(10):11091118

Cisplatin nephrotoxicity and protection by milk thistle extract in rats