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[14] [15] While the relationship between weight loss magnitude and bone loss is complex, patients with more substantial weight reduction may require closer monitoring

Note: If you experience sudden, severe pain in your back or abdomen, or if your aches are accompanied by a high fever, seek medical attention immediately

Any cloudiness may indicate aggregation or microbial contamination Visible particles or floaters particulate matter suspended in the solution is a clear sign of degradation or contamination Discolouration yellowing or browning of the solution suggests oxidative degradation of amino acid residues Gel-like or viscous consistency peptide aggregation can occasionally produce a thickened solution Compromised vial or packaging integrity any damage to the vial, stopper, or seal is grounds for immediate discard Beyond visual inspection, time elapsed since reconstitution is itself a critical consideration

The FASEB Journal (2006)