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In a meta-analysis that pooled findings from six randomized controlled trials with a total of 301 participants, vitamin D was found to reduce migraine frequency, number of days affected by migraine, and migraine-related disability scores (Hu 2021)

2010, titled Genetic, epigenetic, and environmental factors in serotonin-associated disease condition, estimates that genetic factors account for up to 40% of the variation in serotonin regulation, making it a significant risk factor

Soft plastic squeeze-bottle containers are typically sterile water, not bacteriostatic bac water comes in glass with metal-crimp seals as a near-universal rule

doi:10.1016/S0021-9258(19)44924-7