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If you stop GLP-1 medications like tirzepatide, research shows several common outcomes: Appetite increases Calories consumed gradually rise Weight regains within weeks to months Blood sugar improvements may diminish This is not a sign of failure, its simply biology

revealed that liraglutide attenuates oxidative stress and albuminuria in streptozotocin (STZ)-diabetic rats via the PKA-mediated inhibition of renal NADPH oxidases (Xu et al., 2014)

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Certain conditions, such as a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2, may mean that GLP-1 medications are not recommended