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doi: 10.3389/fmicb.2022.1002084 87 BalloutJAkibaYKaunitzJDSchwiertzAMazzuoli-WeberGBrevesGet al

Step 3 High-Shear Homogenization & Sizing We engineer the particle size to ensure dermal penetration while minimizing thermal stress on the peptide: Cold-process high-pressure homogenization to prevent heat-induced hydrolysis of the peptide bond

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Multiple SRCR domains in a single polypeptide or in oligomers may enable high-avidity interactions with weak binding sites on diverse ligands