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Factors like baseline metabolic rate, previous weight loss attempts, and medication consistency influence individual outcomes

Despite the proliferation of research that has expanded our understanding of TBI epidemiology and pathogenesis, the updated consensus for clinical management in the hospital setting does not define reliable biomarkers or drug therapies aimed at directly limiting secondary brain injury [11, 12]

A recent large-scale clinical trial has confirmed that tirzepatide, a dual GIP and GLP-1RAs, resulted in a weight loss of up to 20.9% in adults with body fat mass of 30 or more after 72-week follow-up [22]

Subcutaneous once weekly