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The effect was observed in both male and female rats at clinically relevant plasma exposures

In its submission to FDA, Eli Lilly and Company relied on these proposed criteria and claimed that tirzepatide, the active ingredient in Mounjaro (tirzepatide) injection and Zepbound (tirzepatide) injection, meets at least two of these proposed criteriafirst because of the complexity of its formulation, and second because of the complexity in its required physiochemical or analytical testing

It uses a series of fat-dissolving micro-injections to break down stubborn fat deposits under the skin and improve circulation

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