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Moreover, concentrations of ACs [hydroxybutyrylcarnitine (C4:0-OH) and hexadecenoylcarnitine (C16:1)] in schizophrenia patients were significantly higher than those in healthy controls, whereas those of C3:0, C8:0, C10:0, C10:1, C10:2, C12:0, hydroxytetradecenoylcarnitine (C14:1-OH), C14:2 and C14:2-OH were lower

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In conclusion, a diverse array of small molecules has been devised to specifically target the enzymatic activity of AKR1C3, offering a promising avenue for impeding its role in carcinoma progression and treatment resistance