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IVD tissue sections were harvested and stained with anti-FSP1 and DAPI and then analyzed by immunofluorescence microscopy

The development of reaction-based AIE sensors is of our current interest and ongoing in our laboratories

The compounds under review are not FDA-approved and will not become so this summer

While specific downregulation kinetics for Dihexa haven't been thoroughly characterized in published literature, research on HGF and c-Met signaling in other contexts suggests receptor density begins declining within 2448 hours of sustained agonist exposure, with maximum downregulation occurring around 72 hours