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One reason for the growing scientific interest is that GHK-Cu appears capable of influencing both structural and functional aspects of tissue health

They are not illegal to buy or own, but they are not approved for human use, so are not subject to the quality controls that govern pharmaceutical manufacturing

The lack of an arginine-stimulated response may therefore reflect a need for a rise in glucagon (which is lost in DT-Gcg mice) for arginine-stimulated somatostatin secretion, whereas GLP-1 may directly stimulate somatostatin through GLP-1 receptors on the delta cells