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Given the importance of purine-containing molecules for survival, vertebrates, including humans, have developed robust systems for synthesizing sufficient purine nucleosides for their metabolism using readily available materials (such as glucose, glycine, and glutamine), as well as recycling purine nucleosides from throughout the body or from the diet

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Obesity treatments using GLP-1 receptor agonists focus on weight management by promoting satiety, thereby reducing food intake and assisting in sustained weight loss