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2p) and a higher percentage of rats with a recognition score 60 Hz) may also be related to increased bursting rates of sub-cortical DA-VTA neurons [97], consistent with our previous evidence showing that adolescent THC treatment leads to persistent hyperactivation and increased bursting rates of DA cells [4, 5, 10]

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The PIONEER 8 study demonstrated the efficacy of once-daily oral semaglutide as an add-on to insulin therapy in people with T2D who were uncontrolled on insulin (with or without metformin)

Dopaminergic medications and neuromodulation have been shown to suppress corticosubcortical beta-band hypersynchronization 24,68,70,71,72