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reported that the specific decrease of KGDHC occurs even in pathologically unaffected areas in PD, and the decrease is unlikely to be a non-specific result of neurodegeneration

Influence on the ability to drive vehicles and mechanisms In view of the possible manifestations of side effects of the drug, the drug should be used with caution in persons driving vehicles and servicing mechanisms

However, none of the treatments could fully restore the disc height or achieve the same MRI T2 signal intensity as the healthy disc [96]

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