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Transcriptional activation of NR4a1 by Creb5 disturbed the balance of glycolipid metabolism and promoted glycolysis and lipid accumulation

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As in our previous study [8], acute dosing with metformin (1000 mg) did not affect fasting glucose concentrations over 60 min, but did reduce the glycaemic response to the intraduodenal glucose load in type 2 diabetes

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