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Description

In each case, a slight change in the drugs target protein prevents binding without abolishing its normal function

In late August 2015, the US FDA issued a warning that drugs like sitagliptin, saxagliptin, linagliptin, alogliptin, and other DPP-4 inhibitors could cause joint pain that can be severe and disabling

These consequences can lead to the development of autoimmune diseases and chronic pain conditions like fibromyalgia