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Pteroic acid is then converted to folic acid through the N -esterification of glutamic acid to the carboxylic acid of the PABA portion of pteroic acid

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Oral doses used in animal studies are typically three to ten times higher than equivalent injectable doses to produce comparable systemic effects suggesting oral bioavailability in the range of 1030% relative to parenteral delivery.3 That does not mean oral BPC-157 is ineffective