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In that study, UA treatment increased the mRNA and protein expression of Nrf2 and three Nrf2-responsive genes, including the g-glutamate-cysteine ligase catalytic subunit, heme oxygenase-1, and NQO1, which are oxidation-related genes involved in redox homeostasis

The N/C ratio decreased to 1/1 when cells reached confluence, i.e

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