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Nat Rev Immunol 15(3):160171

Although compounds such as vitamins, polyphenols, and plant-derived molecules have demonstrated promise in preliminary studies, more comprehensive clinical trials are needed to confirm their therapeutic value, determine optimal dosages, and assess long-term safety

In addition, over the course of time, certain novel bioactive compounds have been explored for their potential as DPP-IV inhibitors through the use of in silico analysis ( Figure 5 )

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