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Chlorogenic acid induces apoptosis to inhibit inflammatory proliferation of IL-6-induced fibroblast-like synoviocytes through modulating the activation of JAK/STAT and NF-B signaling pathways

Statements Data availability statement The original contributions presented in the study are included in the article/supplementary material

These abnormalities can be eliminated by either reexpressing WT TANGO2 or CRISPR correction of the specific mutation, supporting the validity of these models

These findings reinforce an important principle: greater pharmacologic strength does not always translate to optimal individual outcomes