Cardiovascular outcome trials have demonstrated significant reductions in major adverse cardiovascular events with certain agents in this class (liraglutide, injectable semaglutide, and dulaglutide), leading to expanded indications for cardiovascular risk reduction
But I follow a couple hundred adults with ADHD, and anecdotally, I have seen a number of patients that have reported feeling better in terms of their ADHD symptoms when they went on GLP-1s. The most popular drugs in the GLP-1 receptor agonist category use either semaglutide, the active ingredient in Ozempic and Wegovy, or tirzepatide, which powers Mounjaro and Zepbound
Ann Intern Med 169(3):165174
Among people who have not taken a GLP-1 drug, about one in five (22%) say they would be interested in taking a GLP-1 drug to lose weight, including 7% who say they would be very interested. Women are more likely than men to say they would be at least somewhat interested in taking these drugs to lose weight (27% v