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Neurobehavioral tests involved 72 mice (12 mice each from Slc25a39 fl/fl + Sham group, Slc25a39 fl/fl + TBI group, Slc25a39 fl/fl + TBI + rFGF21 group, Slc25a39 CKO + Sham group, Slc25a39 CKO + TBI group, and Slc25a39CKO + TBI + rFGF21 group)

Injections may seem more inconvenient

The results with semaglutide alone are encouraging and suggest a potential new treatment option for a group of patients who previously had very few. The Phase II trial followed about 700 adults with biopsy-confirmed MASH and moderate to advanced liver scarring, including participants who had already developed early cirrhosis