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Gradual dose increase: Starting with a low dose and gradually increasing it can help minimize side effects

Closure methods included in the code The AMAs CPT guidelines are explicit that codes 12001-13160 designate closure utilizing sutures, staples or tissue adhesive (e.g., 2-cyanoacrylate), either singly or in combination with each other, or in combination with adhesive strips. This matters for practices that use Steri-Strips or tissue adhesive as the primary closure method

Adv Pharmacol 1997;38:65-7 6

Clinical studies report that the topical application of Argireline can significantly reduce wrinkle depth and appearance compared to placebo