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Neurons are the most abundant cell population in the CNS and are highly susceptible to hypoxia

NOX1-derived ROS drive the expression of Lipocalin-2 in colonic epithelial cells in inflammatory conditions

Proc Natl Acad Sci U S A 1987, 84: 34343438

In September 2023, the FDA did update the semaglutide label to add ileus (a severe intestinal blockage) as a warning, demonstrating that the agency does act on emerging safety signals when the evidence supports it