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For instance, the expression levels of specific genes have been correlated with symptom severity, offering promising avenues for targeted clinical interventions [296]

376,377 Obesity is a metabolic disorder caused by genetic, environmental, and other factors, which is related to a variety of metabolic diseases, such as diabetes, hypertension, cardiovascular, and cerebrovascular diseases

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PD0325901 (Mirdametinib) Mirdametinib (PD0325901) is a selective and non ATP-competitive MEK inhibitor with IC50 of 0.33 nM in cell-free assays, roughly 500-fold more potent than CI-1040 on phosphorylation of ERK1 and ERK2