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194 In addition, adenovirus-mediated gene transfer of wild-type AXIN1 induces HCC cell and CRC cell apoptosis, which is blocked by APC, CTNNB1, or AXIN1 mutations

Stool Softeners / Emollients Examples: Docusate sodium, Liquid paraffin Mechanism: Reduce surface tension allow water and fat to penetrate stool Uses: Painful or hard stools, post-surgery, hemorrhoids Adverse Effects: Rare: diarrhea, mild cramping 5

The most serious of which is that it causes several serious conditions, including gastroparesis

Moreover, experimental models have hinted at the direct anti-proliferative and pro-apoptotic activities of GLP-1 analogs on cancerous cells, suggesting that these agents may actively interfere with malignant cell signaling pathways and tumor microenvironment dynamics