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When multiple CALMs are present, the possibility of a neurocutaneous syndrome, most commonly neurofibromatosis type 1, needs to be considered whereas generalized lentiginosis may point to the diagnosis of Carney complex or Noonan syndrome with multiple lentigines (LEOPARD syndrome)

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In this case, pharmacies are buying semaglutide, the active ingredient in Wegovy and Ozempic, and tirzepatide, the active ingredient in Zepbound

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