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Subgroup analyses showed significant between-study heterogeneity in studies conducted in all subgroups that were not probable sources of heterogeneity (Table 3)

RA was diagnosed based on the American College of Rheumatology (ACR) guidelines and the severity of rheumatoid arthritis (RA) was assessed according to the Disease Activity Score 28 (DAS 28)

However, they each target these incretins differently