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Ggele, M

Genetic mutations in genes codifying for the cytochrome c oxidase are related to fatal metabolic disorders [64] which particularly affect tissues and organs with high energy demand, such as the heart

Both hypothesized factors, elevated arousal-related neuromodulation and a relative shortfall of brain uptake, would predict a widespread effect on tCho levels, which corresponds to the reduced tCho seen generally across cortical regions in AnxDs