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1 Introduction Osteoarthritis (OA) is among the most prevalent degenerative joint diseases globally, affecting more than 500 million people worldwide and ranking as the leading cause of disability among adults aged 50 years and older ( Ferroptosis, first reported in 2012, is a novel form of cell death distinct from classical apoptosis, pyroptosis, and necrosis ( Due to the possible critical role of ferroptosis in OA, there has been a surge of interest in elucidating its molecular mechanisms and exploring potential therapeutic strategies

To get the lowdown on everything from what happens to your body during a session to the risks involved, we asked three medical experts to weigh in: Dena Westphalen, PharmD, a clinical pharmacist, Lindsay Slowiczek, PharmD, a drug information pharmacist, and Debra Sullivan, PhD, MSN, RN, CNE, COI, a nurse educator who specializes in complementary and alternative medicine, pediatrics, dermatology, and cardiology

Q2: How is Adequan i.m