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Candace Steele, a spokesperson, said, Were exploring its possibilities to treat excessive sleepiness associated with schizophrenia, bipolar depression, traumatic injury, and jet lag. Though she emphasized that Cephalon was not developing Nuvigil as a neuroenhancer, she noted, As part of the preparation for some of these other diseases, were looking to see if theres improvement in cognition. Unlike many hypothetical scenarios that bioethicists worry abouthuman clones, designer babiescognitive enhancement is already in full swing

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Notably, conversion of aconitate to itaconate via aconitate decarboxylase (ACOD1) that activates downstream KEAP1/NRF2 signaling and inflammatory response pathway are well known under inflammatory conditions 103,104

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