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Figure 4d and e depict volcano plots highlighting the variations in tirzepatide-related signals across dose subgroups (2.5 mg, 5.0 mg and 7.5 mg, the three most common doses)

Recent evidence has highlighted the role of oxidative stress and neuronal dysfunction in the pathogenesis of peripheral neuropathy, providing a rationale for exploring agents with neuroprotective and antioxidant properties 10

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It is not approved for human or veterinary use and should not be used for consumption, compounding, treatment, or clinical application