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The integrated analysis of five clinical trials in stage 3 T1D in evaluating the efficacy and safety of teplizumab over the last 20 years showed significantly greater C peptide levels at 1 and 2 years post-treatment in patients treated with teplizumab than in control patients, which implies preservation of cell function

Next, we performed correlation analysis adjusting for age and sex to identify any associations between neuroinflammatory and BBB dysfunction markers with BBB permeability assessed using DCE-MRI

Despite all these findings, it remains unclear whether dietary cholesterol could be classified as a risk factor for promoting a more immunosuppressive tumor microenvironment