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Semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, works by slowing gastric emptying and signaling fullness to the braineffects that strengthen as your body adjusts to higher doses

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They found treatment with semaglutide/tirzepatide improved body composition by reducing excess body fat, including abdominal fat, and increasing the proportion of lean body mass, or the amount of weight someone carries that is not body fat

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