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FIGURE 3 Low bioavailability remains a major hurdle for harnessing the therapeutic benefits of PCs, necessitating innovative delivery approaches such as nano-encapsulation, phospholipid complexation, and co-administration with permeability enhancers

Overdose of B12 can cause anxiety, acne, skin redness, headache, nausea, vomiting, heart stroke, face paralysis, palpitations, facial ruddiness, and insomnia

This approach involved homogenising and dividing sperm suspensions from each individual male across all experimental treatments ( Figure 2 )

demonstrated that although the combination therapy (metformin 1000 mg BID + liraglutide 1.2 mg/day) resulted in a greater weight loss than liraglutide alone, both groups showed an increase in SHBG and a decrease in free testosterone, with no differences between the two treatment arms, thus suggesting that the effect on the biochemical hyperandrogenism of liraglutide may be partially independent of the extent of weight loss [60]