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In a cohort of 74 patients with biopsy-proven NASH, 48-week treatment with rosiglitazone combined with diet and physical activity, compared to diet and exercise alone, was shown to significantly ameliorate NAS, steatosis, and ballooning, but no effect was detected on fibrosis [45]

Both routes are heading to the same destination: PCAC review before February 2027, where the committee will evaluate whether GHK-Cu (in both forms) should be added to the 503A compounding list