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What should be keep in mind, alcohol abuse and smoking, not least through redox imbalances may lead to the deterioration of the oral cavity homeostasis

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The multidrug resistance protein 1 (Mrp1), but not Mrp5, mediates export of glutathione and glutathione disulfide from brain astrocytes

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However, eNOS is also expressed in erythrocytes, and erythrocyte-derived NO may impact their deformability and suppress platelet activation [171, 172]

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