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In: Annual Progress in Child Psychiatry and Child Development 20002001

3,28 One approach is to prevent degradation by DPP-IV through amino acid substitutions, as this enzyme preferentially cleaves N-terminal Xaa-Pro or Xaa-Ala sequences

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SIRT1 is also known as the "longevity gene" because of its role in reducing the risk of diabetes, obesity, metabolic syndrome, atherosclerosis and other forms of cardiovascular disease, kidney disease, liver disease, neurodegeneration, and cancer