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Based on preclinical studies, a systematic review of the neuroprotective mechanisms of GLP-1RA-based therapy in ischemic stroke [67] has shown that administration of drugs of this family before, during, or after an experimental stroke in animals with and without diabetes modulates an acute inflammatory response secondary to brain ischemia, reducing inflammation, endothelial dysfunction and excitotoxicity, as well as decreasing oxidative stress and apoptosis

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Comp Biochem Physiol 151C:229239 Rust AJ, Burgess RM, Brownawell BJ, McElroy AE (2004) Relationship between metabolism and bioaccumulation of benzo[a]pyrene in benthic invertebrates

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