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In summary, future clinical trials should prioritize enrolling individuals at risk, followed by those in the early stages of the disease, as this offers a higher likelihood of demonstrating neuroprotective and disease-modifying effects

10.3389/fimmu.2023.1148209 53 MengF.WangK.AoyamaT.GrivennikovS

Conducted among both healthy individuals and patients with type 2 diabetes, the MGH trial showed that GLP-1 (7-37) had potent insulinotropic effects in both groups