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You can use it with other medicines, but it is always advised to consult with a healthcare professional before using any supplement with other medicines

The FDAs current guidance, updated June 15, 2026, is blunt about what the category means: compounded GLP-1s skip the agencys review for safety, effectiveness, and quality entirely, and as of May 31, 2026 the FDA had logged 990 adverse-event reports for compounded semaglutide and more than 730 for compounded tirzepatide, per the FDAs compounded GLP-1 page

Healthcare providers may prescribe Rybelsus and metformin together to maximize glycemic control

Regardless of the site, clean the area thoroughly with an alcohol swab and let it air dry