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Monitoring Strategy: Baseline ECG before starting retatrutide Monitor heart rate at follow-up visits Consider dose reduction if resting HR exceeds 100 bpm Hold medication if patient develops symptomatic tachycardia Long-Term Cardiovascular Safety Questions TRIUMPH-4 provides 68 weeks of data

Govindappagari, Shravya, et al

People use the term 'withdrawal' to describe everything from rebound oxidative stress to actual physical dependency, and those are completely different biological events

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