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Singhs study including 44 patients demonstrated that lycopene was superior than intralesional injection of betamethasone in improving mouth opening and burning sensation ( Besides, three studies have analyzed and compared the therapeutic effects between lycopene and curcumin ( Additionally, in comparison to aloe vera which is another antioxidant, lycopene exhibited better therapeutic effects in treating OSF (Sudarshan et al., 2012)

10.1038/nrm.2016.140 241 Saint-GermainE.MignaccaL.VernierM.BobbalaD.IlangumaranS.FerbeyreG